Motif ID: FOS_FOS{B,L1}_JUN{B,D}.p2

Z-value: 3.672


Transcription factors associated with FOS_FOS{B,L1}_JUN{B,D}.p2:

Gene SymbolEntrez IDGene Name
FOS 2353 v-fos FBJ murine osteosarcoma viral oncogene homolog
FOSB 2354 FBJ murine osteosarcoma viral oncogene homolog B
FOSL1 8061 FOS-like antigen 1
JUNB 3726 jun B proto-oncogene
JUND 3727 jun D proto-oncogene

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOSchr14_+_757454800.831.2e-02Click!
JUNDchr19_-_18392436-0.724.2e-02Click!
FOSL1chr11_-_656678090.502.1e-01Click!
FOSBchr19_+_45971249-0.403.3e-01Click!
JUNBchr19_+_129022950.196.6e-01Click!


Activity profile for motif FOS_FOS{B,L1}_JUN{B,D}.p2.

activity profile for motif FOS_FOS{B,L1}_JUN{B,D}.p2


Sorted Z-values histogram for motif FOS_FOS{B,L1}_JUN{B,D}.p2

Sorted Z-values for motif FOS_FOS{B,L1}_JUN{B,D}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOS_FOS{B,L1}_JUN{B,D}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr18_+_21452981 25.467 NM_000227
NM_001127718
 LAMA3

laminin, alpha 3

chr1_+_183155173 17.394 NM_005562
NM_018891
 LAMC2

laminin, gamma 2

chr1_+_153003677 14.830 NM_003125
 SPRR1B
small proline-rich protein 1B
chr1_+_183155361 14.685 LAMC2
laminin, gamma 2
chr1_+_183155393 13.402 LAMC2
laminin, gamma 2
chr3_-_151034514 12.904 NM_023915
 GPR87
G protein-coupled receptor 87
chr20_+_44637539 11.044 NM_004994
 MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr12_-_52886971 10.117 NM_005554
 KRT6A
keratin 6A
chr19_-_51523272 9.993 NM_002776
NM_001077500
 KLK10

kallikrein-related peptidase 10

chr15_+_40532034 8.798 NM_020168
 PAK6
p21 protein (Cdc42/Rac)-activated kinase 6
chr6_+_47666288 8.531 NM_153838
 GPR115
G protein-coupled receptor 115
chr18_+_61442611 8.255 NM_003784
 SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr11_+_394199 8.192 NM_007183
 PKP3
plakophilin 3
chr11_+_394238 7.886 PKP3
plakophilin 3
chr2_+_47596447 7.832 EPCAM
epithelial cell adhesion molecule
chr11_-_118134986 7.778 MPZL2
myelin protein zero-like 2
chr18_+_61554938 7.666 NM_001143818
NM_002575
 SERPINB2

serpin peptidase inhibitor, clade B (ovalbumin), member 2

chr11_-_118134956 7.579 MPZL2
myelin protein zero-like 2
chr10_+_118187381 7.360 NM_001011709
 PNLIPRP3
pancreatic lipase-related protein 3
chr7_+_73245192 7.304 NM_001305
 CLDN4
claudin 4

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 12 of 12 entries
enrichment   p-value GO term description
2.61 6.20e-04 GO:0008544 epidermis development
1.47 2.18e-02 GO:0035556 intracellular signal transduction
1.35 5.01e-05 GO:0007165 signal transduction
1.32 1.18e-04 GO:0023052 signaling
1.31 2.27e-02 GO:0048731 system development
1.29 2.26e-02 GO:0048856 anatomical structure development
1.27 1.41e-03 GO:0051716 cellular response to stimulus
1.27 1.10e-02 GO:0032502 developmental process
1.19 1.23e-02 GO:0050896 response to stimulus
1.18 3.23e-03 GO:0050794 regulation of cellular process
1.17 1.99e-03 GO:0065007 biological regulation
1.17 5.48e-03 GO:0050789 regulation of biological process

Gene overrepresentation in compartment category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
6.25 1.63e-03 GO:0001533 cornified envelope

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
1.52 2.18e-02 GO:0030234 enzyme regulator activity